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Prenatal FISH Probes

Approximately 75% of chromosomal abnormalities detected in prenatal screening are aneuploidies involving chromosomes 13, 18, 21, X, or Y. FISH has proven a consistently accurate method of detecting these aneusomies, as well as other conditions that are tough to analyze based on conventional karyotyping alone (i.e. low level mosaicism, microdeletions, microduplications, and cryptic translocations). The 3 most important factors to consider during fetal karyotype analysis - resolution level, the time required to obtain analyzable metaphases, and sufficient number of cells – are also easily met by FISH.

Empire Genomics' probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads. These products are for research use only (RUO) and are not for use in diagnostic procedures.


Chromosome 18 Enumeration Probe

Region: 18p11.1-q11.1

Chromosome X Enumeration Probe

Region: Xq11.1

Chromosome Y Enumeration Probe

Region: Yp11.1 - Yq11.1

Chromosome 13 Enumeration Probe

Region: 13q21.31

Chromosome 21 Enumeration Probe

Region: 21q21.1

Chromosomes X and Y Enumeration Probes

Region: Xq11.1, Yp11.1-q11.1