Break Apart FISH Probes

Break-apart probes are designed to detect translocations, the most common genetic abnormality exhibited in cancer cells. With new gene rearrangements being continuously discovered, and their oncogenic effects elucidated, translocations have become essential cancer biomarkers.

Our dual-colored break-apart FISH probes have helped thousands of researchers quickly and reliably track gene translocations. They’re designed to flank either side of a gene, so that in the event of a translocation, the two colors will split. Each kit contains 20 tests and normally ships within 1-3 weeks. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads. These products are for research use only (RUO) and are not for use in diagnostic procedures.