Empire Genomics' AR probe is designed to detect AR amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AR-20-OR  (Standard Design) 20 (40 μL) 200 μL
AR-20-BIO 20 (40 μL) 200 μL
AR-20-DNP 20 (40 μL) 200 μL
AR-20-RE 20 (40 μL) 200 μL
AR-20-AQ 20 (40 μL) 200 μL
AR-20-DIG 20 (40 μL) 200 μL
AR-20-GR 20 (40 μL) 200 μL
AR-20-GO 20 (40 μL) 200 μL

Gene Summary

The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract from the normal 9-34 repeats to the pathogenic 38-62 repeats causes spinal bulbar muscular atrophy (SBMA, also known as Kennedy's disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2017]

Gene Details

Gene Symbol: AR

Gene Name: Androgen Receptor

Chromosome: CHRX: 66763873-66944119

Locus: Xq12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.