GRM1 Break Apart FISH Probe
Our GRM1 break apart probe is designed to detect GRM1 translocations. The probe comes labeled in orange and green, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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GRM1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
GRM1BA-20-GOGR | 20 (40 μL) | 200 μL | ||
GRM1BA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Gene Details
Gene Symbol: GRM1
Gene Name: Glutamate Metabotropic Receptor 1
Chromosome: CHR6: 146348781-146758731
Locus: 6q24.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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