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ABCB1 FISH Probe

Our ABCB1 probe is designed to detect ABCB1 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs. 

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABCB1-20-OR  (Standard Design) 20 (40 μL) 200 μL
ABCB1-20-RE 20 (40 μL) 200 μL
ABCB1-20-AQ 20 (40 μL) 200 μL
ABCB1-20-GR 20 (40 μL) 200 μL
ABCB1-20-GO 20 (40 μL) 200 μL

Gene Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. Mutations in this gene are associated with colchicine resistance and Inflammatory bowel disease 13. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Feb 2017]

Gene Details

Gene Symbol: ABCB1

Gene Name: ATP Binding Cassette Subfamily B Member 1

Chromosome: CHR7: 87133178-87342639

Locus: 7q21.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.