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NTRK2 Break Apart FISH Probe

Our NTRK2 Break Apart Probe is designed to detect NTRK translocations. The probe comes labeled in orange and green but can be customized to meet your needs.

Gene Background: NTRK2 is a receptor tyrosine kinase that binds brain-derived growth factor (BDGF) and neurotrophin 4/5 (NT-4/5). The gene is essential to central and peripheral nervous system development and cell survival. NTRK2 rearrangements have been detected in many cancers, including glioblastoma, pilocytic astrocytoma, head and neck squamous cell carcinoma, and lung adenocarcinoma. These rearrangements generate fusion genes encoding hybrid proteins with ligand-independent TK activity, leading to unchecked cell proliferation and tumorigenesis.

Source: Amatu A, et al. (2016) ESMO open 1.2: e000023.

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping

Download FISH Protocol Download Material Safety Data Sheet

SKU Test Kits Buffer Dye Color Order Now
NTRK2BA-20-ORGR  (Standard Design) 20 (40μL) 200 μL
NTRK2BA-20-GOGR 20 (40μL) 200 μL
NTRK2BA-20-GRGO 20 (40μL) 200 μL
NTRK2BA-20-REGR 20 (40μL) 200 μL
NTRK2BA-20-REGO 20 (40μL) 200 μL