NOTCH2 FISH Probe
Empire Genomics has developed a NOTCH2 FISH Probe which can be used to detect NOTCH2 gene aneusomy. The probe comes labeled in orange, and you may also choose to customize the probe to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NOTCH2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| NOTCH2-20-GO | 20 (40 μL) | 200 μL |
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| NOTCH2-20-GR | 20 (40 μL) | 200 μL |
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| NOTCH2-20-AQ | 20 (40 μL) | 200 μL |
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| NOTCH2-20-RE | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the Notch family. Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple, different domain types. Notch family members play a role in a variety of developmental processes by controlling cell fate decisions. The Notch signaling network is an evolutionarily conserved intercellular signaling pathway which regulates interactions between physically adjacent cells. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signaling pathway that plays a key role in development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remain to be determined. This protein is cleaved in the trans-Golgi network, and presented on the cell surface as a heterodimer. This protein functions as a receptor for membrane bound ligands, and may play a role in vascular, renal and hepatic development. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Details
Gene Symbol: NOTCH2
Gene Name: Notch 2
Chromosome: CHR1: 120454175-120612317
Locus: 1p12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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