ROS1 Break Apart Extended FISH Probe
Empire Genomics' ROS1 Break Apart extended probe to detect a translocations of the ROS1 gene at chromosomal region 6q221.1. Extended break apart probes have longer probe lengths than their standard break apart counterparts. This is intended to amplify signal intensity, making the probes easier to visualize under the microscope. The probe comes labeled in green and orange, but can be cusomized to meet your needs.
Gene Background: The ROS1 gene codes for the ROS1 tyrosine kinase insulin receptor, a type I integral membrane protein that binds cell growth and differentiation signaling factors.1 Rearrangements of ROS1 have been implicated in a multitude of cancers, including NSCLC, gastric cancer, ovarian cancer, colorectal cancer, and various epithelial malignancies.2 These translocations produce fusion proteins, constitutively activating the kinase domain of ROS1.3
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
|SKU||Test Kits||Buffer||Dye Color||Order Now|
|ROS1BA-EXT-20-GROR (Standard Design)||20 (40 μL)||200 μL|
FISH Probe Protocols
|Protocol, Procedure, or Form Name||Last Modified||Download|