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NTRK1 Break Apart FISH Probe

Our NTRK1 Break Apart probe is designed to detect NTRK1 translocations. The probe comes labeled in orange and green, but can be customized to meet your needs. 

Gene Background: NTRK1, which belongs to the same neurotrophin receptor family that includes NTRK2 and NTRK3, encodes a tyrosine kinase that binds nerve growth factor (NGF). The gene is critical to central and peripheral nervous system development, helping to regulate proliferation, differentiation, and apoptosis in neural cells. NTRK1 rearrangements, which generally result in fusions with partner genes that constitutively activate NTRK1’s kinase domain, have been identified in a number of human cancers. These include colon carcinoma, papillary thyroid carcinoma, lung cancer, glioblastoma, and melanoma.

Source: Amatu A, et al. (2016) ESMO open 1.2: e000023.

Available as CE marked product in certain countries

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping

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SKU Test Kits Buffer Dye Color Order Now
NTRK1BA-20-ORGR  (Standard Design) 20 (40μL) 200 μL
NTRK1BA-20-GOGR 20 (40μL) 200 μL
NTRK1BA-20-GRRE 20 (40μL) 200 μL
NTRK1BA-20-REGR 20 (40μL) 200 μL
NTRK1BA-20-REGO 20 (40μL) 200 μL
NTRK1BA-20-GROR 20 (40μL) 200 μL
NTRK1BA-20-GRGO 20 (40μL) 200 μL