FGFR3/IGH Split FISH Probe
Our FGFR3/IGH split probe is designed to detect fusions between FGFR3 and IGH. To account for the high degree of cross homology in the region containing IGH, part of the IGH portion has been removed. The probe comes labeled in orange and green, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FGFR3-IGH-Split-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FGFR3-IGH-Split-20-GOGR | 20 (40 μL) | 200 μL |
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| FGFR3-IGH-Split-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: FGFR3
Gene Name: Fibroblast Growth Factor Receptor 3
Chromosome: CHR4: 1795038-1810599
Locus: 4p16.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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