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FGFR3/IGH Split FISH Probe

Our FGFR3/IGH split probe is designed to detect fusions between FGFR3 and IGH. To account for the high degree of cross homology in the region containing IGH, part of the IGH portion has been removed. The probe comes labeled in orange and green, but can be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FGFR3-IGH-Split-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
FGFR3-IGH-Split-20-GOGR 20 (40 μL) 200 μL
FGFR3-IGH-Split-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: FGFR3

Gene Name: Fibroblast Growth Factor Receptor 3

Chromosome: CHR4: 1795038-1810599

Locus: 4p16.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.