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FISH Probe Products & Services
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RP11-486K17 FISH Probe

The RP11-486K17 FISH Probe is sold in 10 test kits and can be labeled in one of five fluorescent dyes. According to the UCSC Genome Browser, the RP11-486K17 BAC clone that would be used to manufacture this FISH probe has coordinates on CHR21: 22397411-22552405 on build hg18 and CHR21: 23475540-23630534 on build hg19 . Typical turnaround time for this product is 7-14 days after purchase. Empire Genomics validates the position of its RP11 confirmatory probes using BAC End Sequencing and does not guarantee that RP11 probes will not cross hybridize to another location.

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Other FISH Probe Products

Custom FISH Probes are developed based on customer specifications by selecting a region covered by the RP-11 or RP-23 library. Custom probes are tested using end sequencing. Batches are tested for FISH signal intensity, but localization cannot be guaranteed beyond end sequencing.

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Gene-Specific FISH Probes hybridize to a precise gene location. They are designed to be used with a control probe unless a dual-color probe is selected. Probes are FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei.

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Chromosome Control Probes are made to hybridize to the peri/centromeric region of a chromosome. They are often used to enumerate chromosomes and can be used as a control to help determine whether another probe is hybridizing to the correct chromosome.

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Disease specific probes are designed to hybridize to the precise location of genes associated with specific diseases, and contain multiple RP11 clones. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads.

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