WT1 FISH Probe
Our WT1 probe is designed to hybridize to the WT1 gene. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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WT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
WT1-20-RE | 20 (40 μL) | 200 μL | ||
WT1-20-AQ | 20 (40 μL) | 200 μL | ||
WT1-20-GR | 20 (40 μL) | 200 μL | ||
WT1-20-GO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]
Gene Details
Gene Symbol: WT1
Gene Name: Wilms Tumor 1
Chromosome: CHR11: 32409321-32457081
Locus: 11p13
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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