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RET Break Apart FISH Probe

Our RET Break Apart Probe is designed to detect RET translocations. The probe comes labeled in orange and green, but can be customized to meet your needs.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RETBA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RETBA-20-GOGR 20 (40 μL) 200 μL
RETBA-20-REGR 20 (40 μL) 200 μL

Gene Summary

This gene encodes a transmembrane receptor and member of the tyrosine protein kinase family of proteins. Binding of ligands such as GDNF (glial cell-line derived neurotrophic factor) and other related proteins to the encoded receptor stimulates receptor dimerization and activation of downstream signaling pathways that play a role in cell differentiation, growth, migration and survival. The encoded receptor is important in development of the nervous system, and the development of organs and tissues derived from the neural crest. This proto-oncogene can undergo oncogenic activation through both cytogenetic rearrangement and activating point mutations. Mutations in this gene are associated with Hirschsprung disease and central hypoventilation syndrome and have been identified in patients with renal agenesis. [provided by RefSeq, Sep 2017]

Gene Details

Gene Symbol: RET

Gene Name: Ret Proto-oncogene

Chromosome: CHR10: 43572516-43625797

Locus: 10q11.21

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.