NUP98 Break Apart FISH Probe
Our NUP98 break apart is designed to detect NUP98 translocations. The probe comes labeled in green and orange, but can be customized to meet your needs.
Gene Background: NUP98 encodes the major component protein of the nuclear pore complex that regulates the nucleocytoplasmic transport of proteins and mRNA. Since the discovery of the first NUP98 fusion with HOXA9 in AML, more than 30 NUP98 partners have been identified in several hematologic diseases, including AML, MDS, CML in blast crisis, ALL, and bilineage/biphenotypic leukemia. NUP98 fusion proteins have oncogenic properties, whereas NUP98 is a potential tumor suppressor and regulates the post-transcriptional expression of certain TP53 target genes.
|SKU||Test Kits||Buffer||Dye Color||Order Now|
|NUP98BA-20-GROR (Standard Design)||20 (40 μL)||200 μL|
|NUP98BA-20-GRRE||20 (40 μL)||200 μL|
|NUP98BA-20-GRGO||20 (40 μL)||200 μL|
FISH Probe Protocols
|Protocol, Procedure, or Form Name||Last Modified||Download|