NFKB2 Break Apart FISH Probe
Our NFKB2 break apart probe is designed to detect NFKB2 translocations. The probe comes labeled in green and orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NFKB2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| NFKB2BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| NFKB2BA-20-GRRE | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Gene Details
Gene Symbol: NFKB2
Gene Name: Nuclear Factor Kappa B Subunit 2
Chromosome: CHR10: 104154228-104162281
Locus: 10q24.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|