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FGFR1 FISH Probe

Our FGFR1 probe is designed to detect FGFR1 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs. 

 

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
FGFR1-20-OR  (Standard Design) 20 (40 μL) 200 μL
FGFR1-20-RE 20 (40 μL) 200 μL
FGFR1-20-AQ 20 (40 μL) 200 μL
FGFR1-20-GR 20 (40 μL) 200 μL
FGFR1-20-GO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: FGFR1

Gene Name: Fibroblast Growth Factor Receptor 1

Chromosome: CHR8: 38268655-38326352

Locus: 8p11.23

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.