CDK4 FISH Probe
Our CDK4 probe is designed to detect CDK4 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CDK4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| CDK4-20-GO | 20 (40 μL) | 200 μL |
|
|
| CDK4-20-GR | 20 (40 μL) | 200 μL |
|
|
| CDK4-20-AQ | 20 (40 μL) | 200 μL |
|
|
| CDK4-20-RE | 20 (40 μL) | 200 μL |
|
Gene Summary
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of this kinase is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). This kinase was shown to be responsible for the phosphorylation of retinoblastoma gene product (Rb). Mutations in this gene as well as in its related proteins including D-type cyclins, p16(INK4a) and Rb were all found to be associated with tumorigenesis of a variety of cancers. Multiple polyadenylation sites of this gene have been reported. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CDK4
Gene Name: Cyclin Dependent Kinase 4
Chromosome: CHR12: 58141509-58146230
Locus: 12q14.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|