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BRCA2 FISH Probe

Our BRCA2 probe is designed to detect BRCA2 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs. 

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
BRCA2-20-OR  (Standard Design) 20 (40 μL) 200 μL
BRCA2-20-RE 20 (40 μL) 200 μL
BRCA2-20-AQ 20 (40 μL) 200 μL
BRCA2-20-GR 20 (40 μL) 200 μL
BRCA2-20-GO 20 (40 μL) 200 μL

Gene Summary

Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]

Gene Details

Gene Symbol: BRCA2

Gene Name: BRCA2, DNA Repair Associated

Chromosome: CHR13: 32889616-32973809

Locus: 13q13.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.