BRCA2 FISH Probe
Our BRCA2 probe is designed to detect BRCA2 amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BRCA2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| BRCA2-20-RE | 20 (40 μL) | 200 μL |
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| BRCA2-20-AQ | 20 (40 μL) | 200 μL |
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| BRCA2-20-GR | 20 (40 μL) | 200 μL |
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| BRCA2-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
Inherited mutations in BRCA1 and this gene, BRCA2, confer increased lifetime risk of developing breast or ovarian cancer. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair. The BRCA2 protein contains several copies of a 70 aa motif called the BRC motif, and these motifs mediate binding to the RAD51 recombinase which functions in DNA repair. BRCA2 is considered a tumor suppressor gene, as tumors with BRCA2 mutations generally exhibit loss of heterozygosity (LOH) of the wild-type allele. [provided by RefSeq, Dec 2008]
Gene Details
Gene Symbol: BRCA2
Gene Name: BRCA2, DNA Repair Associated
Chromosome: CHR13: 32889616-32973809
Locus: 13q13.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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