BRAF FISH Probe
Our BRAF FISH probe is designed to detect BRAF amplifications and deletions. The probe comes labeled in orange, but can be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| BRAF-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| BRAF-20-RE | 20 (40 μL) | 200 μL |
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| BRAF-20-AQ | 20 (40 μL) | 200 μL |
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| BRAF-20-GR | 20 (40 μL) | 200 μL |
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| BRAF-20-GO | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: BRAF
Gene Name: B-Raf Proto-oncogene, Serine/threonine Kinase
Chromosome: CHR7: 140433812-140624564
Locus: 7q34
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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