ABL2 Break Apart FISH Probe
Our ABL2 break apart probe is designed to detect ABL2 translocations. The probe comes labeled in orange and green, but can be customized to meet your needs.
Gene Background: ABL2 belongs to the same gene family of Abelson nonreceptor tyrosine kinases as ABL1. It regulates actin rearrangement via phosphorylation of cytoskeleton-remodeling proteins, including MYH10, CTTN, and TUBB. ABL2 rearrangements have been identified in several leukemias, often resulting in fusions with ETV6.
Source: GeneCards.org
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ABL2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ABL2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| ABL2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| ABL2BA-20-GROR | 20 (40 μL) | 200 μL |
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| ABL2BA-20-REGR | 20 (40 μL) | 200 μL |
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| ABL2BA-20-GRRE | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Gene Details
Gene Symbol: ABL2
Gene Name: ABL Proto-oncogene 2, Non-receptor Tyrosine Kinase
Chromosome: CHR1: 179068461-179198819
Locus: 1q25.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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