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ABL1 Break Apart FISH Probe

The ABL1 gene, located on chromosome 9q34.1, is activated by being translocated within the BCR (breakpoint cluster region) gene on chromosome 22. The t(9;22) translocation is present in ~90% of chronic myelogeneous leukemia (CML) cases. The chromosomal abnormality, t(9;22)(q34;q11.2), involving the ABL1, BCR, and ASS1 genes, is observed in ~95% of CML, ~20% of cases of adult acute lymphoblastic leukemia (ALL), ~4% of cases of childhood ALL, and ~3% of acute myeloid leukemia (AML).

Our ABL1 Break Apart FISH Probe can be used to detect a rearrangement of the ABL1 gene. The probe comes labeled in green and orange, and you may also choose to customize the probe to meet your needs.

SKU Test Kits Buffer Dye Color Order Now
ABL1BA-20-GROR  (Standard Design) 20 (40 μL) 200 μL
ABL1BA-20-GRGO 20 (40 μL) 200 μL
ABL1BA-20-GRRE 20 (40 μL) 200 μL