ZBTB33 FISH Probe
The ZBTB33 FISH probe is designed to hybridize to the ZBTB33 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZBTB33-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ZBTB33-20-RE | 20 (40 μL) | 200 μL |  |
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| ZBTB33-20-GO | 20 (40 μL) | 200 μL |  |
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| ZBTB33-20-GR | 20 (40 μL) | 200 μL |  |
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| ZBTB33-20-AQ | 20 (40 μL) | 200 μL |  |
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| ZBTB33-20-DIG | 20 (40 μL) | 200 μL |  |
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| ZBTB33-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-α2 (also known as karyopherin alpha2 or RAG cohort 1), which may mediate nuclear import of this protein. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, May 2010]
Gene Details
Gene Symbol: ZBTB33
Gene Name: Zinc Finger And BTB Domain Containing 33
Chromosome: CHRX: 119384606-119392251
Locus: Xq24
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ZBTB33 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ZBTB33-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping