XPC Break Apart FISH Probe
Empire Genomics’ XPC Break Apart FISH Probe is designed to flank the XPC gene and is typically used for detecting XPC rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| XPCBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| XPCBA-20-AQOR | 20 (40 μL) | 200 μL |
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| XPCBA-20-GOGR | 20 (40 μL) | 200 μL |
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| XPCBA-20-GORE | 20 (40 μL) | 200 μL |
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| XPCBA-20-GRGO | 20 (40 μL) | 200 μL |
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| XPCBA-20-GRRE | 20 (40 μL) | 200 μL |
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| XPCBA-20-ORGR | 20 (40 μL) | 200 μL |
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| XPCBA-20-REGO | 20 (40 μL) | 200 μL |
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| XPCBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: XPC
Gene Name: XPC Complex Subunit, DNA Damage Recognition And Repair Factor
Chromosome: CHR3: 14186647-14220172
Locus: 3p25.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: XPC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: XPC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping