XPA FISH Probe
The XPA FISH probe is designed to hybridize to the XPA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| XPA-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| XPA-20-RE | 20 (40 μL) | 200 μL |  |
|
| XPA-20-GO | 20 (40 μL) | 200 μL |  |
|
| XPA-20-GR | 20 (40 μL) | 200 μL |  |
|
| XPA-20-AQ | 20 (40 μL) | 200 μL |  |
|
| XPA-20-DIG | 20 (40 μL) | 200 μL |  |
|
| XPA-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a zinc finger protein plays a central role in nucleotide excision repair (NER), a specialized type of DNA repair. NER is responsible for repair of UV radiation-induced photoproducts and DNA adducts induced by chemical carcinogens and chemotherapeutic drugs. The encoded protein interacts with DNA and several NER proteins, acting as a scaffold to assemble the NER incision complex at sites of DNA damage. Mutations in this gene cause Xeroderma pigmentosum complementation group A (XP-A), an autosomal recessive skin disorder featuring hypersensitivity to sunlight and increased risk for skin cancer. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: XPA
Gene Name: XPA, DNA Damage Recognition And Repair Factor
Chromosome: CHR9: 100437190-100459691
Locus: 9q22.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: XPA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: XPA-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping