XIAP FISH Probe
The XIAP FISH probe is designed to hybridize to the XIAP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| XIAP-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| XIAP-20-RE | 20 (40 μL) | 200 μL |  |
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| XIAP-20-GO | 20 (40 μL) | 200 μL |  |
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| XIAP-20-GR | 20 (40 μL) | 200 μL |  |
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| XIAP-20-AQ | 20 (40 μL) | 200 μL |  |
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| XIAP-20-DIG | 20 (40 μL) | 200 μL |  |
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| XIAP-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: XIAP
Gene Name: X-linked Inhibitor Of Apoptosis
Chromosome: CHRX: 122993661-123047829
Locus: Xq25
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: XIAP FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: XIAP-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping