WT1 FISH Probe
The WT1 FISH probe is designed to hybridize to the WT1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
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| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| WT1-20-RE | 20 (40 μL) | 200 μL |  |
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| WT1-20-GO | 20 (40 μL) | 200 μL |  |
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| WT1-20-GR | 20 (40 μL) | 200 μL |  |
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| WT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| WT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| WT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilms tumor. This gene exhibits complex tissue-specific and polymorphic imprinting pattern, with biallelic, and monoallelic expression from the maternal and paternal alleles in different tissues. Multiple transcript variants have been described. In several variants, there is evidence for the use of a non-AUG (CUG) translation initiation codon upstream of, and in-frame with the first AUG. Authors of PMID:7926762 also provide evidence that WT1 mRNA undergoes RNA editing in human and rat, and that this process is tissue-restricted and developmentally regulated. [provided by RefSeq, Mar 2015]
Gene Details
Gene Symbol: WT1
Gene Name: Wilms Tumor 1
Chromosome: CHR11: 32409321-32457081
Locus: 11p13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: WT1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: WT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping