WRN FISH Probe
The WRN FISH probe is designed to hybridize to the WRN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| WRN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| WRN-20-RE | 20 (40 μL) | 200 μL |  |
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| WRN-20-GO | 20 (40 μL) | 200 μL |  |
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| WRN-20-GR | 20 (40 μL) | 200 μL |  |
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| WRN-20-AQ | 20 (40 μL) | 200 μL |  |
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| WRN-20-DIG | 20 (40 μL) | 200 μL |  |
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| WRN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the RecQ subfamily of DNA helicase proteins. The encoded nuclear protein is important in the maintenance of genome stability and plays a role in DNA repair, replication, transcription and telomere maintenance. This protein contains a N-terminal 3' to 5' exonuclease domain, an ATP-dependent helicase domain and RQC (RecQ helicase conserved region) domain in its central region, and a C-terminal HRDC (helicase RNase D C-terminal) domain and nuclear localization signal. Defects in this gene are the cause of Werner syndrome, an autosomal recessive disorder characterized by accelerated aging and an elevated risk for certain cancers. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: WRN
Gene Name: Werner Syndrome RecQ Like Helicase
Chromosome: CHR8: 30890777-31031277
Locus: 8p12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: WRN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: WRN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping