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WRB FISH Probe

The WRB FISH probe is designed to hybridize to the WRB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
WRB-20-OR  (Standard Design) 20 (40 μL) 200 μL
WRB-20-RE 20 (40 μL) 200 μL
WRB-20-GO 20 (40 μL) 200 μL
WRB-20-GR 20 (40 μL) 200 μL
WRB-20-AQ 20 (40 μL) 200 μL
WRB-20-DIG 20 (40 μL) 200 μL
WRB-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene is located in the candidate region for congenital heart disease (CHD) in Down syndrome (DS). It encodes a basic protein that functions as a receptor that promotes insertion of tail-anchored proteins in the endoplasmic reticulum membrane. This gene is located at a maternally-methylated differentially methylated region (DMR); however, its transcription may be biallelic, not imprinted. Alternative splicing results in different transcript variants. A pseudogene has been defined on chromosome 4. [provided by RefSeq, Apr 2017]

Gene Details

Gene Symbol: WRB

Gene Name: Tryptophan Rich Basic Protein

Chromosome: CHR21: 40752212-40769815

Locus: 21q22.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: WRB FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: WRB-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping