WBS FISH Probe
The WBS FISH probe is designed to hybridize to the WBS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ELN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ELN-20-RE | 20 (40 μL) | 200 μL |  |
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| ELN-20-GO | 20 (40 μL) | 200 μL |  |
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| ELN-20-GR | 20 (40 μL) | 200 μL |  |
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| ELN-20-AQ | 20 (40 μL) | 200 μL |  |
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| ELN-20-DIG | 20 (40 μL) | 200 μL |  |
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| ELN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that is one of the two components of elastic fibers. Elastic fibers comprise part of the extracellular matrix and confer elasticity to organs and tissues including the heart, skin, lungs, ligaments, and blood vessels. The encoded protein is rich in hydrophobic amino acids such as glycine and proline, which form mobile hydrophobic regions bounded by crosslinks between lysine residues. Degradation products of the encoded protein, known as elastin-derived peptides or elastokines, bind the elastin receptor complex and other receptors and stimulate migration and proliferation of monocytes and skin fibroblasts. Elastokines can also contribute to cancer progression. Deletions and mutations in this gene are associated with supravalvular aortic stenosis (SVAS) and autosomal dominant cutis laxa. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: ELN
Gene Name: Elastin
Chromosome: CHR7: 73442426-73484236
Locus: 7q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: WBS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ELN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping