WAS Break Apart FISH Probe
Empire Genomics’ WAS Break Apart FISH Probe is designed to flank the WAS gene and is typically used for detecting WAS rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| WASBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| WASBA-20-AQOR | 20 (40 μL) | 200 μL |
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| WASBA-20-GOGR | 20 (40 μL) | 200 μL |
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| WASBA-20-GORE | 20 (40 μL) | 200 μL |
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| WASBA-20-GRGO | 20 (40 μL) | 200 μL |
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| WASBA-20-GROR | 20 (40 μL) | 200 μL |
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| WASBA-20-GRRE | 20 (40 μL) | 200 μL |
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| WASBA-20-REGO | 20 (40 μL) | 200 μL |
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| WASBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: WAS
Gene Name: Wiskott-Aldrich Syndrome
Chromosome: CHRX: 48542185-48549817
Locus: Xp11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: WAS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: WAS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping