VKORC1 FISH Probe
The VKORC1 FISH probe is designed to hybridize to the VKORC1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VKORC1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| VKORC1-20-RE | 20 (40 μL) | 200 μL |  |
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| VKORC1-20-GO | 20 (40 μL) | 200 μL |  |
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| VKORC1-20-GR | 20 (40 μL) | 200 μL |  |
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| VKORC1-20-AQ | 20 (40 μL) | 200 μL |  |
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| VKORC1-20-DIG | 20 (40 μL) | 200 μL |  |
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| VKORC1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the catalytic subunit of the vitamin K epoxide reductase complex, which is responsible for the reduction of inactive vitamin K 2,3-epoxide to active vitamin K in the endoplasmic reticulum membrane. Vitamin K is a required co-factor for carboxylation of glutamic acid residues by vitamin K-dependent gamma-carboxylase in blood-clotting enzymes. Allelic variation in this gene is associated with vitamin k-dependent clotting factors combined deficiency of 2, and increased resistance or sensitivity to warfarin, an inhibitor of vitamin K epoxide reductase. Pseudogenes of this gene are located on chromosomes 1 and X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015]
Gene Details
Gene Symbol: VKORC1
Gene Name: Vitamin K Epoxide Reductase Complex Subunit 1
Chromosome: CHR16: 31102174-31106276
Locus: 16p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: VKORC1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: VKORC1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping