VDR FISH Probe
The VDR FISH probe is designed to hybridize to the VDR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VDR-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| VDR-20-RE | 20 (40 μL) | 200 μL |  |
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| VDR-20-GO | 20 (40 μL) | 200 μL |  |
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| VDR-20-GR | 20 (40 μL) | 200 μL |  |
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| VDR-20-AQ | 20 (40 μL) | 200 μL |  |
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| VDR-20-DIG | 20 (40 μL) | 200 μL |  |
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| VDR-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding different proteins. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: VDR
Gene Name: Vitamin D Receptor
Chromosome: CHR12: 48235319-48298814
Locus: 12q13.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: VDR FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: VDR-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping