VCXC FISH Probe
The VCXC FISH probe is designed to hybridize to the VCXC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VCX3B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| VCX3B-20-RE | 20 (40 μL) | 200 μL |  |
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| VCX3B-20-GO | 20 (40 μL) | 200 μL |  |
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| VCX3B-20-GR | 20 (40 μL) | 200 μL |  |
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| VCX3B-20-AQ | 20 (40 μL) | 200 μL |  |
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| VCX3B-20-DIG | 20 (40 μL) | 200 μL |  |
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| VCX3B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22, and the Y-linked members are two identical copies of the gene within a palindromic region on chromosome Yq11. The family members share a high degree of sequence identity, with the exception that a 30-nt unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. This family member, as represented by the reference genome allele, contains 14 copies of the 30-nt repeat unit. VCX/Y genes encode small and highly charged proteins containing putative bipartite nuclear localization signals. Although the exact function of this family member has yet to be determined, a role in mRNA stability regulation can be inferred from the ability of the highly similar family member, VCX-A, to inhibit mRNA decapping. A possible role in the regulation of ribosome assembly during spermatogenesis has also been suggested. [provided by RefSeq, Aug 2010]
Gene Details
Gene Symbol: VCX3B
Gene Name: Variable Charge, X-linked 3B
Chromosome: CHRX: 8432870-8434551
Locus: Xp22.31
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: VCXC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: VCX3B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping