VAV1 FISH Probe
The VAV1 FISH probe is designed to hybridize to the VAV1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VAV1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| VAV1-20-RE | 20 (40 μL) | 200 μL |  |
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| VAV1-20-GO | 20 (40 μL) | 200 μL |  |
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| VAV1-20-GR | 20 (40 μL) | 200 μL |  |
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| VAV1-20-AQ | 20 (40 μL) | 200 μL |  |
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| VAV1-20-DIG | 20 (40 μL) | 200 μL |  |
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| VAV1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. The encoded protein is important in hematopoiesis, playing a role in T-cell and B-cell development and activation. The encoded protein has been identified as the specific binding partner of Nef proteins from HIV-1. Coexpression and binding of these partners initiates profound morphological changes, cytoskeletal rearrangements and the JNK/SAPK signaling cascade, leading to increased levels of viral transcription and replication. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
Gene Details
Gene Symbol: VAV1
Gene Name: Vav Guanine Nucleotide Exchange Factor 1
Chromosome: CHR19: 6772721-6857371
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: VAV1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: VAV1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping