UTRN FISH Probe
The UTRN FISH probe is designed to hybridize to the UTRN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UTRN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UTRN-20-RE | 20 (40 μL) | 200 μL |  |
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| UTRN-20-GO | 20 (40 μL) | 200 μL |  |
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| UTRN-20-GR | 20 (40 μL) | 200 μL |  |
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| UTRN-20-AQ | 20 (40 μL) | 200 μL |  |
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| UTRN-20-DIG | 20 (40 μL) | 200 μL |  |
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| UTRN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene shares both structural and functional similarities with the dystrophin gene. It contains an actin-binding N-terminus, a triple coiled-coil repeat central region, and a C-terminus that consists of protein-protein interaction motifs which interact with dystroglycan protein components. The protein encoded by this gene is located at the neuromuscular synapse and myotendinous junctions, where it participates in post-synaptic membrane maintenance and acetylcholine receptor clustering. Mouse studies suggest that this gene may serve as a functional substitute for the dystrophin gene and therefore, may serve as a potential therapeutic alternative to muscular dystrophy which is caused by mutations in the dystrophin gene. Alternative splicing of the utrophin gene has been described; however, the full-length nature of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: UTRN
Gene Name: Utrophin
Chromosome: CHR6: 144612872-145174170
Locus: 6q24.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: UTRN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UTRN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping