USP20 Break Apart FISH Probe
Empire Genomics’ USP20 Break Apart FISH Probe is designed to flank the USP20 gene and is typically used for detecting USP20 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP20BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP20BA-20-AQOR | 20 (40 μL) | 200 μL |
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| USP20BA-20-GOGR | 20 (40 μL) | 200 μL |
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| USP20BA-20-GORE | 20 (40 μL) | 200 μL |
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| USP20BA-20-GRGO | 20 (40 μL) | 200 μL |
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| USP20BA-20-GROR | 20 (40 μL) | 200 μL |
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| USP20BA-20-GRRE | 20 (40 μL) | 200 μL |
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| USP20BA-20-REGO | 20 (40 μL) | 200 μL |
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| USP20BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]
Gene Details
Gene Symbol: USP20
Gene Name: Ubiquitin Specific Peptidase 20
Chromosome: CHR9: 132597695-132644107
Locus: 9q34.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: USP20 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: USP20-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping