USP2 FISH Probe
The USP2 FISH probe is designed to hybridize to the USP2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| USP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| USP2-20-RE | 20 (40 μL) | 200 μL |  |
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| USP2-20-GO | 20 (40 μL) | 200 μL |  |
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| USP2-20-GR | 20 (40 μL) | 200 μL |  |
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| USP2-20-AQ | 20 (40 μL) | 200 μL |  |
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| USP2-20-DIG | 20 (40 μL) | 200 μL |  |
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| USP2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the family of de-ubiquitinating enzymes, which belongs to the peptidase C19 superfamily. The encoded protein is a ubiquitin-specific protease which is required for TNF-alpha (tumor necrosis factor alpha) -induced NF-kB (nuclear factor kB) signaling. This protein deubiquitinates polyubiquitinated target proteins such as fatty acid synthase, murine double minute 2 (MDM2), MDM4/MDMX and cyclin D1. MDM2 and MDM4 are negative regulators of the p53 tumor suppressor and cyclin D1 is required for cell cycle G1/S transition. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Details
Gene Symbol: USP2
Gene Name: Ubiquitin Specific Peptidase 2
Chromosome: CHR11: 119225924-119252436
Locus: 11q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: USP2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: USP2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping