USP18 Break Apart FISH Probe
Empire Genomics’ USP18 Break Apart FISH Probe is designed to flank the USP18 gene and is typically used for detecting USP18 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| USP18BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| USP18BA-20-AQOR | 20 (40 μL) | 200 μL |
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| USP18BA-20-GOGR | 20 (40 μL) | 200 μL |
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| USP18BA-20-GORE | 20 (40 μL) | 200 μL |
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| USP18BA-20-GRGO | 20 (40 μL) | 200 μL |
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| USP18BA-20-GROR | 20 (40 μL) | 200 μL |
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| USP18BA-20-GRRE | 20 (40 μL) | 200 μL |
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| USP18BA-20-REGO | 20 (40 μL) | 200 μL |
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| USP18BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: USP18
Gene Name: Ubiquitin Specific Peptidase 18
Chromosome: CHR22: 18632757-18660162
Locus: 22q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: USP18 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: USP18-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping