USP18 FISH Probe
The USP18 FISH probe is designed to hybridize to the USP18 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| USP18-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| USP18-20-RE | 20 (40 μL) | 200 μL |  |
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| USP18-20-GO | 20 (40 μL) | 200 μL |  |
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| USP18-20-GR | 20 (40 μL) | 200 μL |  |
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| USP18-20-AQ | 20 (40 μL) | 200 μL |  |
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| USP18-20-DIG | 20 (40 μL) | 200 μL |  |
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| USP18-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011]
Gene Details
Gene Symbol: USP18
Gene Name: Ubiquitin Specific Peptidase 18
Chromosome: CHR22: 18632757-18660162
Locus: 22q11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: USP18 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: USP18-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping