UPF2 Break Apart FISH Probe
Empire Genomics’ UPF2 Break Apart FISH Probe is designed to flank the UPF2 gene and is typically used for detecting UPF2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UPF2BA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| UPF2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| UPF2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| UPF2BA-20-GORE | 20 (40 μL) | 200 μL |
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| UPF2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| UPF2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| UPF2BA-20-ORGR | 20 (40 μL) | 200 μL |
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| UPF2BA-20-REGO | 20 (40 μL) | 200 μL |
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| UPF2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located in the perinuclear area. It interacts with translation release factors and the proteins that are functional homologs of yeast Upf1p and Upf3p. Two splice variants have been found for this gene; both variants encode the same protein. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: UPF2
Gene Name: UPF2, Regulator Of Nonsense Mediated MRNA Decay
Chromosome: CHR10: 11962021-12085023
Locus: 10p14
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: UPF2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UPF2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping