UNC45B Break Apart FISH Probe
Empire Genomics’ UNC45B Break Apart FISH Probe is designed to flank the UNC45B gene and is typically used for detecting UNC45B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| UNC45BBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| UNC45BBA-20-AQOR | 20 (40 μL) | 200 μL |
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| UNC45BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| UNC45BBA-20-GORE | 20 (40 μL) | 200 μL |
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| UNC45BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| UNC45BBA-20-GROR | 20 (40 μL) | 200 μL |
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| UNC45BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| UNC45BBA-20-REGO | 20 (40 μL) | 200 μL |
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| UNC45BBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Details
Gene Symbol: UNC45B
Gene Name: Unc-45 Myosin Chaperone B
Chromosome: CHR17: 33474835-33516364
Locus: 17q12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: UNC45B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UNC45B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping