UNC45B FISH Probe
The UNC45B FISH probe is designed to hybridize to the UNC45B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UNC45B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UNC45B-20-RE | 20 (40 μL) | 200 μL |  |
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| UNC45B-20-GO | 20 (40 μL) | 200 μL |  |
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| UNC45B-20-GR | 20 (40 μL) | 200 μL |  |
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| UNC45B-20-AQ | 20 (40 μL) | 200 μL |  |
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| UNC45B-20-DIG | 20 (40 μL) | 200 μL |  |
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| UNC45B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a co-chaperone required for folding and accumulation of type II myosins. The protein consists of three tetratricopeptide repeat motifs at the N-terminus that form a complex with heat shock protein 90, a central region of unknown function that is conserved in all Unc-45 proteins, and a C-terminal Unc-45/Cro1/She4 domain. The protein is expressed at high levels in striated muscle, where its muscle myosin chaperone activity is dependent on heat shock protein 90 acting as a co-chaperone. A missense mutation in this gene has been associated with cataract development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]
Gene Details
Gene Symbol: UNC45B
Gene Name: Unc-45 Myosin Chaperone B
Chromosome: CHR17: 33474835-33516364
Locus: 17q12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: UNC45B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UNC45B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping