UNC13B FISH Probe
The UNC13B FISH probe is designed to hybridize to the UNC13B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UNC13B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| UNC13B-20-RE | 20 (40 μL) | 200 μL |  |
|
| UNC13B-20-GO | 20 (40 μL) | 200 μL |  |
|
| UNC13B-20-GR | 20 (40 μL) | 200 μL |  |
|
| UNC13B-20-AQ | 20 (40 μL) | 200 μL |  |
|
| UNC13B-20-DIG | 20 (40 μL) | 200 μL |  |
|
| UNC13B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is expressed in the kidney cortical epithelial cells and is upregulated by hyperglycemia. The encoded protein shares a high level of similarity to the rat homolog, and contains 3 C2 domains and a diacylglycerol-binding C1 domain. Hyperglycemia increases the levels of diacylglycerol, which has been shown to induce apoptosis in cells transfected with this gene and thus contribute to the renal cell complications of hyperglycemia. Studies in other species also indicate a role for this protein in the priming step of synaptic vesicle exocytosis. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: UNC13B
Gene Name: Unc-13 Homolog B
Chromosome: CHR9: 35161988-35405332
Locus: 9p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: UNC13B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UNC13B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping