UMOD Break Apart FISH Probe
Empire Genomics’ UMOD Break Apart FISH Probe is designed to flank the UMOD gene and is typically used for detecting UMOD rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
UMODBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL | ||
UMODBA-20-AQOR | 20 (40 μL) | 200 μL | ||
UMODBA-20-GOGR | 20 (40 μL) | 200 μL | ||
UMODBA-20-GORE | 20 (40 μL) | 200 μL | ||
UMODBA-20-GRGO | 20 (40 μL) | 200 μL | ||
UMODBA-20-GRRE | 20 (40 μL) | 200 μL | ||
UMODBA-20-ORGR | 20 (40 μL) | 200 μL | ||
UMODBA-20-REGO | 20 (40 μL) | 200 μL | ||
UMODBA-20-REGR | 20 (40 μL) | 200 μL |
Gene Summary
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: UMOD
Gene Name: Uromodulin
Chromosome: CHR16: 20344372-20364037
Locus: 16p12.3
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
---|
Customer Publications
Product Details
Product: UMOD FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UMOD-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping