UGT1A4 Break Apart FISH Probe
Empire Genomics’ UGT1A4 Break Apart FISH Probe is designed to flank the UGT1A4 gene and is typically used for detecting UGT1A4 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UGT1A4BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| UGT1A4BA-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| UGT1A4BA-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| UGT1A4BA-20-GORE | 20 (40 μL) | 200 μL |
|
|
| UGT1A4BA-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| UGT1A4BA-20-GROR | 20 (40 μL) | 200 μL |
|
|
| UGT1A4BA-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| UGT1A4BA-20-REGO | 20 (40 μL) | 200 μL |
|
|
| UGT1A4BA-20-REGR | 20 (40 μL) | 200 μL |
|
Gene Summary
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: UGT1A4
Gene Name: UDP Glucuronosyltransferase Family 1 Member A4
Chromosome: CHR2: 234627437-234681945
Locus: 2q37.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: UGT1A4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UGT1A4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping