UCP3 FISH Probe
The UCP3 FISH probe is designed to hybridize to the UCP3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UCP3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UCP3-20-RE | 20 (40 μL) | 200 μL |  |
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| UCP3-20-GO | 20 (40 μL) | 200 μL |  |
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| UCP3-20-GR | 20 (40 μL) | 200 μL |  |
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| UCP3-20-AQ | 20 (40 μL) | 200 μL |  |
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| UCP3-20-DIG | 20 (40 μL) | 200 μL |  |
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| UCP3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. The different UCPs have tissue-specific expression; this gene is primarily expressed in skeletal muscle. This gene's protein product is postulated to protect mitochondria against lipid-induced oxidative stress. Expression levels of this gene increase when fatty acid supplies to mitochondria exceed their oxidation capacity and the protein enables the export of fatty acids from mitochondria. UCPs contain the three solcar protein domains typically found in MACPs. Two splice variants have been found for this gene.[provided by RefSeq, Nov 2008]
Gene Details
Gene Symbol: UCP3
Gene Name: Uncoupling Protein 3
Chromosome: CHR11: 73711325-73720282
Locus: 11q13.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: UCP3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UCP3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping