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UBE3B FISH Probe

The UBE3B FISH probe is designed to hybridize to the UBE3B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
UBE3B-20-OR  (Standard Design) 20 (40 μL) 200 μL
UBE3B-20-RE 20 (40 μL) 200 μL
UBE3B-20-GO 20 (40 μL) 200 μL
UBE3B-20-GR 20 (40 μL) 200 μL
UBE3B-20-AQ 20 (40 μL) 200 μL
UBE3B-20-DIG 20 (40 μL) 200 μL
UBE3B-20-BIO 20 (40 μL) 200 μL

Gene Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin-protein ligases. This gene encodes a member of the E3 ubiquitin-conjugating enzyme family which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme and transfers the ubiquitin to the targeted substrates. A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases. Shorter isoforms of this protein which lack the C-terminal HECT domain are therefore unlikely to bind E2 enzymes. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2012]

Gene Details

Gene Symbol: UBE3B

Gene Name: Ubiquitin Protein Ligase E3B

Chromosome: CHR12: 109915438-109974507

Locus: 12q24.11

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: UBE3B FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: UBE3B-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping