UBB FISH Probe
The UBB FISH probe is designed to hybridize to the UBB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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UBB-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
UBB-20-RE | 20 (40 μL) | 200 μL | ||
UBB-20-GO | 20 (40 μL) | 200 μL | ||
UBB-20-GR | 20 (40 μL) | 200 μL | ||
UBB-20-AQ | 20 (40 μL) | 200 μL | ||
UBB-20-DIG | 20 (40 μL) | 200 μL | ||
UBB-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimer's disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Details
Gene Symbol: UBB
Gene Name: Ubiquitin B
Chromosome: CHR17: 16284366-16286054
Locus: 17p11.2
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: UBB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UBB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping