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TYMS FISH Probe

The TYMS FISH probe is designed to hybridize to the TYMS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TYMS-20-OR  (Standard Design) 20 (40 μL) 200 μL
TYMS-20-RE 20 (40 μL) 200 μL
TYMS-20-GO 20 (40 μL) 200 μL
TYMS-20-GR 20 (40 μL) 200 μL
TYMS-20-AQ 20 (40 μL) 200 μL
TYMS-20-DIG 20 (40 μL) 200 μL
TYMS-20-BIO 20 (40 μL) 200 μL

Gene Summary

Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using, 10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occurring antisense transcript, mitochondrial enolase superfamily member 1 (GeneID:55556), vary inversely when cell-growth progresses from late-log to plateau phase. Polymorphisms in this gene may be associated with etiology of neoplasia, including breast cancer, and response to chemotherapy. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: TYMS

Gene Name: Thymidylate Synthetase

Chromosome: CHR18: 657603-673499

Locus: 18p11.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: TYMS FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TYMS-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping