TXNRD1 Break Apart FISH Probe
Empire Genomics’ TXNRD1 Break Apart FISH Probe is designed to flank the TXNRD1 gene and is typically used for detecting TXNRD1 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TXNRD1BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TXNRD1BA-20-AQOR | 20 (40 μL) | 200 μL |
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| TXNRD1BA-20-GOGR | 20 (40 μL) | 200 μL |
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| TXNRD1BA-20-GORE | 20 (40 μL) | 200 μL |
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| TXNRD1BA-20-GRGO | 20 (40 μL) | 200 μL |
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| TXNRD1BA-20-GROR | 20 (40 μL) | 200 μL |
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| TXNRD1BA-20-GRRE | 20 (40 μL) | 200 μL |
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| TXNRD1BA-20-REGO | 20 (40 μL) | 200 μL |
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| TXNRD1BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The protein encoded by this gene belongs to the pyridine nucleotide-disulfide oxidoreductase family, and is a member of the thioredoxin (Trx) system. Three thioredoxin reductase (TrxR) isozymes are found in mammals. TrxRs are selenocysteine-containing flavoenzymes, which reduce thioredoxins, as well as other substrates, and play a key role in redox homoeostasis. This gene encodes an ubiquitously expressed, cytosolic form of TrxR, which functions as a homodimer containing FAD, and selenocysteine (Sec) at the active site. Sec is encoded by UGA codon that normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing, primarily at the 5' end, results in transcript variants encoding same or different isoforms, including a glutaredoxin-containing isoform that is predominantly expressed in testis. [provided by RefSeq, May 2017]
Gene Details
Gene Symbol: TXNRD1
Gene Name: Thioredoxin Reductase 1
Chromosome: CHR12: 104609558-104744062
Locus: 12q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TXNRD1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TXNRD1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping